OpenEvidence

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OpenEvidence: Fast, sourced medical answers for healthcare pros. Access 1M+ topics across 160 specialties, grounded in peer-reviewed literature.0
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What is OpenEvidence?

Navigating the vast landscape of medical information to find accurate, up-to-date answers at the point of care can be a significant challenge. You need reliable information, quickly, to make the best decisions for your patients. OpenEvidence serves as your dedicated medical information platform, providing healthcare professionals like you with precise, sourced answers, directly grounded in peer-reviewed medical literature.

OpenEvidence is designed exclusively for healthcare professionals, and verification of your status (e.g., NPI) is required for access, ensuring a community dedicated to high-quality medical information exchange. As Dr. Ram Dandillaya, Clinical Chief of Cardiology at Cedars-Sinai, puts it, OpenEvidence is "more up-to-date than UpToDate... It’s like having a curbside consult with a team of expert physicians, but that you can carry around with you in your pocket."

Your Comprehensive Medical Knowledge Hub

OpenEvidence equips you with the tools and information necessary to enhance your clinical practice and stay current.

  • 📚 Access Extensive, Sourced Content: Delve into information spanning 160 medical specialties, covering over 1,000 diseases and therapeutic areas, and more than 1 million medical topics. Every piece of information is meticulously sourced and cited.

  • 🌟 Integrate NEJM Expertise: Benefit from newly included content from the New England Journal of Medicine (NEJM), including published articles, multimedia resources, and invited review articles from world-renowned clinical experts.

  • 🔍 Pinpoint Information with Powerful Search: Utilize a highly intuitive user interface and a robust medical search engine that understands your clinical questions, helping you discover exactly what you need without sifting through irrelevant results. As Dr. John Lee, Physician & Faculty Member at Harvard Medical School, notes, "Able to narrow down on results quickly and find information that I wasn't able to do with Google/PubMed searches on my own.”

  • 📱 Consult On-the-Go: With its mobile-native platform, OpenEvidence ensures the world’s most powerful medical search engine is always at your fingertips, whether you're on rounds, in your office, or preparing for a case.

  • ✅ Trust in Verified Information: Feel confident in your clinical decisions, knowing that every answer on OpenEvidence is grounded in peer-reviewed medical literature. This commitment to evidence-based medicine is why Nobel Laureate Daniel Kahneman recognized OpenEvidence's efforts as "invaluable" in making medicine more evidence-based.

OpenEvidence in Your Daily Practice

Imagine these scenarios:

  1. Clarifying a Complex Diagnosis: You're seeing a patient with an unusual constellation of symptoms. You can quickly consult OpenEvidence on your tablet, input the specific clinical picture, and receive a sourced summary of potential diagnoses, relevant NEJM review articles, and management considerations, helping you refine your approach at the point of care.

  2. Preparing for a Challenging Case: A resident is preparing for grand rounds on a patient with a rare endocrine disorder. Using OpenEvidence, they can dive deep into the pathophysiology, explore the latest therapeutic guidelines, and review expert opinions, ensuring they are thoroughly prepared to discuss the case with senior colleagues.

  3. Staying Abreast of New Treatments: An oncologist in community practice, like C.J., who calls OpenEvidence "an incredible lifeline for daily practitioners," wants to ensure their treatment protocols for a specific malignancy reflect the most current research. They regularly use OpenEvidence to search for recent NEJM publications and updates in their field, integrating the latest evidence into their patient care strategies.

Your Partner in Evidence-Based Medicine

OpenEvidence is more than just a database; it's a partner in your commitment to providing the highest standard of care. Trusted by medical professionals in over 10,000 care centers across the United States, it offers a reliable, efficient way to access the medical knowledge you need, when you need it. Dr. Antonio Jorge Forte, Director of MayoExpert at Mayo Clinic, believes "OpenEvidence can be the foundational technology to power all clinical decision tools.”


More information on OpenEvidence

Launched
2004-01
Pricing Model
Free
Starting Price
Global Rank
Follow
Month Visit
<5k
Tech used
Google Fonts,Next.js,Vercel,Emotion,Gzip,OpenGraph,Webpack,HSTS,Google Cloud Storage,Apple App Banner
OpenEvidence was manually vetted by our editorial team and was first featured on 2025-05-11.
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